PHYGE team

The PHYGE team’s research focuses on understanding microbial physiology under environmental constraints through an integrative approach. This approach combines methods and tools from quantitative physiology—including biochemical, molecular, and biophysical techniques—with those from biochemical engineering, such as bioreactor operation and nutritional strategies. The goal is to characterize microbial phenotypes under conditions relevant to intensive bioproduction.

Two major axes are addressed:

• Axe I: « “Understanding and engineering microbial cells for functional food, feed and health” focuses on understanding microbial physiology and interactions for functional foods and industrial biotechnology.
• Axe II: “Understanding cell heterogeneity for mastering robustness in bioproduction” aims at understanding cell heterogeneity to master the robustness of microbial strains under intensive bioproduction conditions.

The primary objective of these research activities is to generate scientific knowledge that can be leveraged in more applied projects in industrial biotechnology and human and animal health.