Biocatalysis department

The Biocatalysis pole is composed of a single team

Research description

Focus on: Enzymes, Binding modules, Transporters

Exploration of natural enzymatic diversity
Study of the Sequence-Structure- Dynamics-Activity-Stability relationships
Computational design and protein engineering
Enzymatic processes, cellular or acellular
Development of sustainable biotechnological solutions

for One Health, synthetic biology and circular economy (biomass valorization, waste recycling, human health, etc…)

Approaches

Protein engineering, rational and combinatorial
Multi-scale structural modelling
Computational design & function prediction
Development of automated learning workflows
Incorporation of unnatural amino acids
Automated and droplet-microfluidics based screening
Enzyme immobilization
Engineering of enzymatic reactions and enzymatic cascades

Department leader

Some key words

Enzyme ; Discovery ; Molecular Modelling & Design ; High Throughput Screening; Engineering, Synthetic biology