MNR team
Nuclear Magnetic Resonance
Nuclear Magnetic Resonance
Our team uses Nuclear Magnetic Resonance (NMR) as an analytical method to elucidate (1) the dynamic evolution of metabolic networks and (2) the mechanistic functioning of enzymes. We develop novel methodology to identify and quantify biochemical reaction networks in cell extracts, notably of micro-organisms with biotechnical application. As for the enzymatic studies, we are mostly interested in degrading enzymes that operate at the surface of insoluble polymers.
The team's topics
- Equipe MetaSys : P. Millard
- CIMES team : M Remaud – C Dumon – C Montanier – G Cioci – S Duquesne
- Metatoul : L Peyriga – E Cahoreau
- Metatoul : JM François
- LPCNO : B Chaudret
- IPBS : JD Pedelacq
- Institut Pasteur de Lille, ERL9002, Integrative Structural Biology
- Carbios
- Pauline Rouan – NMR of active cell extracts
Thèses récentes
- Neil Cox : « Suivi en temps réel d’extraits cellulaires par RMN pour comprendre et optimiser les systèmes métaboliques : étude du contrôle exercé par les cofacteurs sur le métabolisme central d’Eschericia coli. » Ecole doctorale SEVAB, le 27 septembre 2022
- Toulouse White Biotechnology (TWB) – ExtractNMR – Real time NMR analysis of biotechnological pathways in cell extracts. 2022-2024 (co-direction with P Millard, EAD6)
- Carbios – Molecular functioning of PETases. 2019- . (C Charlier – G Lippens)
- Flexible Isotope Exchange (FLIX) FET Open – 2019-2023 (G Lippens)
- Multiparametric Strategies against Antibiotic Resistance in Tuberculosis (Mustart) – Projet ANR 2022-2025 (G Lippens)