Physiology and engineering of microbial metabolism department
Physiology and engineering of microbial metabolism department
- PEEP: Engineering and Metabolic Pathway Evolution in Prokaryotes
- I2M: Molecular and Metabolic Engineering
- BLADE: Bacterial Adaptation, Diversity and Engineering
- PHYGE: Integrated physiology and functional genomics of yeast and filamentous fungi
- METASYS: Integrated metabolism and dynamics of metabolic systems
- RMN: Nuclear magnetic resonance
Research description
The core activity of the cluster is the characterization of the molecular basis of microbial metabolisms, both natural and synthetic, and its applications in sustainable biotechnology. The cluster's teams rely on their mastery of growth conditions and their skills in identifying and quantifying the molecular entities that make up microorganisms. These data are used to feed systems biology strategies that help to understand how biological systems work in detail. This knowledge is finally used to optimize the performance of these systems (production, new functions, robustness)
Approaches
1- Analysis: targeted or omic analysis in controlled cultures.
2- Understanding: systems biology strategies.
3- Optimize: combinatorial or rational engineering, synthetic biology, evolution in vivo.
Department leader
