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Physiology and engineering of microbial metabolism department

Research description

The core activity of the cluster is the characterization of the molecular basis of microbial metabolisms, both natural and synthetic, and its applications in sustainable biotechnology. The cluster's teams rely on their mastery of growth conditions and their skills in identifying and quantifying the molecular entities that make up microorganisms. These data are used to feed systems biology strategies that help to understand how biological systems work in detail. This knowledge is finally used to optimize the performance of these systems (production, new functions, robustness)


1- Analysis: targeted or omic analysis in controlled cultures.

2- Understanding: systems biology strategies.

3- Optimize: combinatorial or rational engineering, synthetic biology, evolution in vivo.

Department leader

Some key words

Physiology, Metabolic Engineering, Systems Biology, Synthetic Biology, Microbiology, Escherichia coli, Saccharomyces cerevisiae, Clostridium acetobutylicum, Lactococcus lactis…