Topic "Adaptation and gene expression regulation"

The research activities in the theme "Adaptation and gene expression regulation" are focused on the study of mRNA dynamics. They aim to better understand the post-transcriptional regulations operating at the levels of mRNA degradation and translation. The team evaluates 1) the extent of post-transcriptional regulations at the genome scale, 2) the molecular mechanisms involved in the regulation of mRNA stability or translation efficiency (determination of actors and regulators, identification of sequence determinants, involvement of UTRs, etc.), and 3) the links between post-transcriptional regulations and the overall functioning of the bacterium (impact on adaptation, links with carbon and energy metabolism, coordination with other cellular processes, etc.).