The links between caloric intake and cancer are known for several animals, including humans, but their generalization to all multicellular organisms remains poorly understood. A study of hydra and zebrafish from France, Canada, Hungary and Australia, published in Scientific Reports, showed that dietary restriction prevented or slowed the development of cancers compared with rich diets. Thus, the impact of resource availability does not lie in the number of cells becoming mutant, but rather in favoring their proliferation once they have appeared.
References
Tissot, S., Guimard, L., Meliani, J., Boutry, J., Dujon, A., Capp, J., Tökölyi, J., Biro, P. A., Beckmann, C., Fontenille, L., Khoa, N. D., Hamede, R., Roche, B., Újvári, B., Nedelcu, A. M., & Thomas, F. The impact of food availability on tumorigenesis is evolutionarily conserved. Scientific Reports, publié le 14/11/23.
Contact TBI
Jean-Pascal Capp capp@insa-toulouse.fr
