Biocatalysis department
The Biocatalysis pole is composed of a single team
Research description
Focus on: Enzymes, Binding modules, Transporters
- Exploration of natural enzymatic diversity
- Study of the Sequence-Structure- Dynamics-Activity-Stability relationships
- Computational design and protein engineering
- Enzymatic processes, cellular or acellular
- Development of sustainable biotechnological solutions
for One Health, synthetic biology and circular economy (biomass valorization, waste recycling, human health, etc…)
Approaches
- Protein engineering, rational and combinatorial
- Multi-scale structural modelling
- Computational design & function prediction
- Development of automated learning workflows
- Incorporation of unnatural amino acids
- Automated and droplet-microfluidics based screening
- Enzyme immobilization
- Engineering of enzymatic reactions and enzymatic cascades
Department leader
Magali REMAUD-SIMEON
Some key words
Enzyme ; Discovery ; Molecular Modelling & Design ; High Throughput Screening; Engineering, Synthetic biology