{"id":1908,"date":"2021-12-09T21:51:05","date_gmt":"2021-12-09T20:51:05","guid":{"rendered":"http:\/\/v2tbi.christelle-labruyere.com\/?p=1908"},"modified":"2022-01-20T11:30:16","modified_gmt":"2022-01-20T10:30:16","slug":"soutenance-de-these-emeline-flajollet","status":"publish","type":"post","link":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-emeline-flajollet\/","title":{"rendered":"Emeline Flajollet Thesis defense"},"content":{"rendered":"
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Th\u00e8se intitul\u00e9e “<\/span>Vers la compr\u00e9hension du fonctionnement des consortia microbiens lignocellulolytiques : contribution des approches m\u00e9ta-omiques et biostatistiques<\/strong>“<\/span><\/p>\n

<\/p>

Travaux dirig\u00e9s par Madame Guillermina HERNANDEZ-RAQUET

<\/p>\n

le vendredi 10 d\u00e9cembre 2021 <\/em><\/strong>\u00e0 9h30
Lieu :   TBI 135 Avenue de Rangueil 31077 TOULOUSE CEDEX 4
Salle : 400\/401<\/p>\n

Composition du jury propos\u00e9<\/strong><\/p><\/center>

<\/p>\n\n\n\n\n\n\n\n\n\n
M. JEAN ARMENGAUD <\/td>\nCEA <\/td>\nRapporteur<\/td>\n<\/tr>\n
M. Olivier CHAPLEUR <\/td>\nINRAE <\/td>\nRapporteur<\/td>\n<\/tr>\n
Mme EVELYNE FORANO <\/td>\nINRAE <\/td>\nRapporteure<\/td>\n<\/tr>\n
Mme GUILLERMINA HERNANDEZ-RAQUET <\/td>\nINRAE <\/td>\nDirectrice de th\u00e8se<\/td>\n<\/tr>\n
M. FADHEL BEN CHAABANE <\/td>\nIFP Energies Nouvelles <\/td>\nExaminateur<\/td>\n<\/tr>\n
Mme Claire DUMAS <\/td>\nINRAE <\/td>\nExaminatrice<\/td>\n<\/tr>\n
Mme Claire DUMON <\/td>\nINRAE <\/td>\nExaminatrice<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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R\u00e9sum\u00e9 :<\/strong>  <\/td>\n<\/tr>\n
La lignocellulose, principal composant des parois v\u00e9g\u00e9tales et sous-produit agricole tr\u00e8s abondant, est une des sources de carbone renouvelable les plus prometteuses pour la production d’\u00e9nergie, de produits chimiques ou de biocarburants. L\u2019utilisation de la lignocellulose pour la production de carboxylates repose sur l’utilisation de consortia microbiens. Pour am\u00e9liorer les rendements de production de carboxylates, ces travaux de th\u00e8se se sont int\u00e9ress\u00e9s \u00e0 i) caract\u00e9riser le fonctionnement des consortia s\u00e9lectionn\u00e9s pour leur potentiel lignocellulolytique \u00e0 partir de diff\u00e9rents \u00e9cosyst\u00e8mes naturels et ii) \u00e0 mieux comprendre leurs r\u00e9ponses fonctionnelles face \u00e0 des changements dans la composition et la structure physicochimique du substrat. Pour cela, des approches d\u2019\u00e9cologie microbienne et des outils multi-omiques ont \u00e9t\u00e9 appliqu\u00e9s. Ainsi, des consortia d\u00e9riv\u00e9s de rumen bovin ou d’intestin de termites ont \u00e9t\u00e9 \u00e9tudi\u00e9s par des approches de m\u00e9tabarcoding 16S et de m\u00e9taprot\u00e9omique comparative label-free. Leurs r\u00e9ponses fonctionnelles, enzymatiques et taxonomiques ont \u00e9t\u00e9 \u00e9valu\u00e9es en utilisant la paille de bl\u00e9 pr\u00e9trait\u00e9e par des m\u00e9thodes m\u00e9caniques et\/ou chimiques. Ces recherches ont permis de mettre en \u00e9vidence le r\u00f4le et la compl\u00e9mentarit\u00e9 des diff\u00e9rentes populations composant les consortia microbiens, ainsi que l\u2019effet des modifications induites par le pr\u00e9traitement du substrat sur la r\u00e9gulation de l\u2019expression des enzymes impliqu\u00e9es dans la bioconversion des carbohydrates (CAZymes) en carboxylates. De plus, un consortium issu de rumen bovin et enrichi sur des r\u00e9sidus de ma\u00efs a \u00e9galement \u00e9t\u00e9 \u00e9tudi\u00e9. L\u2019\u00e9tude de la dynamique des populations bact\u00e9riennes au cours de l\u2019enrichissement et de la bioconversion de la lignocellulose a permis de mettre en lumi\u00e8re le r\u00f4le des microorganismes libres et attach\u00e9s au substrat, et de leurs enzymes, fournissant un aper\u00e7u in\u00e9dit du fonctionnement des communaut\u00e9s lignocellulolytiques en bior\u00e9acteur.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

December 10th, 2021<\/p>","protected":false},"author":1,"featured_media":1909,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[19],"class_list":["post-1908","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evenement","tag-equipe-symbiose"],"yoast_head":"\nSoutenance de th\u00e8se - Emeline Flajollet | TBI, Toulouse Biotechnology Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-emeline-flajollet\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Soutenance de th\u00e8se - Emeline Flajollet | TBI, Toulouse Biotechnology Institute\" \/>\n<meta property=\"og:description\" content=\"10 d\u00e9cembre 2021\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-emeline-flajollet\/\" \/>\n<meta property=\"og:site_name\" content=\"TBI, Toulouse Biotechnology Institute\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/TBI-Toulouse-Biotechnology-Institute-Bio-Chemical-Engineering-360428497952306\" \/>\n<meta property=\"article:published_time\" content=\"2021-12-09T20:51:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-01-20T10:30:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2021\/12\/SOUTENANCE-DE-THESE.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Christelle\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@TBI_Biotech\" \/>\n<meta name=\"twitter:site\" content=\"@TBI_Biotech\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Christelle\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-emeline-flajollet\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-emeline-flajollet\\\/\"},\"author\":{\"name\":\"Christelle\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#\\\/schema\\\/person\\\/925c08c7f4d7092aa300f21b872c6dfe\"},\"headline\":\"Soutenance de th\u00e8se – Emeline Flajollet\",\"datePublished\":\"2021-12-09T20:51:05+00:00\",\"dateModified\":\"2022-01-20T10:30:16+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-emeline-flajollet\\\/\"},\"wordCount\":443,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-emeline-flajollet\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/wp-content\\\/uploads\\\/2021\\\/12\\\/SOUTENANCE-DE-THESE.jpg\",\"keywords\":[\"Equipe Symbiose\"],\"articleSection\":[\"Ev\u00e9nement\"],\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-emeline-flajollet\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-emeline-flajollet\\\/\",\"url\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-emeline-flajollet\\\/\",\"name\":\"Soutenance de th\u00e8se - 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