{"id":17447,"date":"2026-02-24T08:00:05","date_gmt":"2026-02-24T07:00:05","guid":{"rendered":"https:\/\/www.toulouse-biotechnology-institute.fr\/?p=17447"},"modified":"2026-03-05T11:11:21","modified_gmt":"2026-03-05T10:11:21","slug":"soutenance-de-these-elise-viau","status":"publish","type":"post","link":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-elise-viau\/","title":{"rendered":"Soutenance de th\u00e8se Elise VIAU"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"17447\" class=\"elementor elementor-17447\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-45db35b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"45db35b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ca9149c\" data-id=\"ca9149c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-36b78a2 elementor-widget elementor-widget-text-editor\" data-id=\"36b78a2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Elise VIAU<\/strong>\u00a0soutiendra sa th\u00e8se, sp\u00e9cialit\u00e9 Ing\u00e9nieries microbienne et enzymatique, sur le th\u00e8me \u00ab\u00a0<em>Bioproduction de compos\u00e9s organiques volatils par Kluyveromyces marxianus : de la mod\u00e9lisation du bioproc\u00e9d\u00e9 au dimensionnement d\u2019une fili\u00e8re biotechnologique durable<\/em>\u00a0\u00bb, le\u00a0<strong>24 f\u00e9vrier 2026 \u00e0 14h,<\/strong>\u00a0salle 401 \u00e0 TBI.<\/p><p><u>Membres du jury<\/u>\u00a0: Sandrine ALFENORE, Emmanuel GUEDON, Pierre FONTANILLE, Carine BIDEAUX, Caroline SABLAYROLLES, Victor POZZOBON, Cristian TRELEA.<\/p><p>\u00a0<\/p><p>Abstract<\/p><p>This thesis was conducted within the framework of the NEW ECO\u2011ROUTES project (ANR\u201121\u2011CE43\u20110012\u201101), which aims to develop a predictive tool for the design of sustainable bioprocesses. This tool will rely on the integration of a biological model, a model for the extraction\/purification step, and an environmental analysis model. As proof of concept, the biological route for converting lignocellulosic biomass into volatile compounds, primarily ethyl acetate (EA), using the yeast Kluyveromyces marxianus was selected.<\/p><p>EA is currently produced almost exclusively through petrochemical routes, despite its widespread use as a solvent. Microbial production remains poorly documented, particularly from lignocellulosic substrates. The main knowledge gaps concerned the lack of quantitative data on xylose and glucose-xylose mixtures, limited information on the impact of substrate availability under iron\u2011limited conditions, and the absence of a stoichiometric metabolic flux analysis (MFA) model for EA biosynthesis.<\/p><p>The main objective of this thesis was to experimentally obtain growth, consumption, and production kinetics of K. marxianus CBS 600 cultivated on glucose and\/or xylose, with a focus on iron limitation as a potential effector of EA biosynthesis. The generated data during this thesis will also support the future development of a relevant biological model for the project. Controlled bioreactor experiments enabled: (i) validation of the iron limitation threshold on glucose and on xylose, (ii) exploration of fed\u2011batch strategies to identify effectors of EA production, (iii) characterization of EA and xylitol dynamics on single and mixed substrates, and (iv) quantification of acetate inhibition independently of iron limitation.<\/p><p>Results confirmed that iron limitation triggers EA synthesis on glucose, accompanied by concomitant ethanol accumulation. Moreover, fed\u2011batch experiments demonstrated that iron is not the sole effector: substrate availability plays a decisive role in regulating metabolic fluxes and conditioning EA biosynthesis. For the first time, EA production by K. marxianus from xylose and glucose-xylose mixtures under iron limitation was quantified under controlled conditions. On xylose alone, EA production remained marginal and unstable, while xylitol emerged as the dominant product and a robust marker of iron stress. In mixed-substrate cultures, a diauxic pattern was confirmed and analysed: EA was mainly formed during the glucose phase, whereas xylitol was produced exclusively from xylose. The subsequent re\u2011consumption of EA highlights the need for an in-situ extraction strategy. Acetate inhibition was quantified separately, affecting growth and ethanol production, while EA remained unaffected.<\/p><p>This thesis thus clarifies the dynamics of K. marxianus on glucose and xylose substrates and identifies possible mechanisms of EA production. The work also enabled the establishment of kinetic equations related to acetate inhibition, and the generation of essential datasets for the calibration and validation of a biological model of EA production. This work contributes to the development of sustainable bioproduction chains and, within this proof of concept, positions EA and xylitol as metabolites of interest for the valorization of C6 and C5 sugars derived from lignocellulosic biomass.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>24 f\u00e9vrier 2026<\/p>","protected":false},"author":1,"featured_media":17448,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,75],"tags":[25],"class_list":["post-17447","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evenement","category-soutenance","tag-equipe-tim"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Soutenance de th\u00e8se Elise VIAU | TBI, Toulouse Biotechnology Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-elise-viau\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Soutenance de th\u00e8se Elise VIAU | TBI, Toulouse Biotechnology Institute\" \/>\n<meta property=\"og:description\" content=\"24 f\u00e9vrier 2026\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-elise-viau\/\" \/>\n<meta property=\"og:site_name\" content=\"TBI, Toulouse Biotechnology Institute\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/TBI-Toulouse-Biotechnology-Institute-Bio-Chemical-Engineering-360428497952306\" \/>\n<meta property=\"article:published_time\" content=\"2026-02-24T07:00:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-05T10:11:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2026\/02\/Soutenance-TBI-1.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Christelle\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@TBI_Biotech\" \/>\n<meta name=\"twitter:site\" content=\"@TBI_Biotech\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Christelle\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/\"},\"author\":{\"name\":\"Christelle\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#\\\/schema\\\/person\\\/925c08c7f4d7092aa300f21b872c6dfe\"},\"headline\":\"Soutenance de th\u00e8se Elise VIAU\",\"datePublished\":\"2026-02-24T07:00:05+00:00\",\"dateModified\":\"2026-03-05T10:11:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/\"},\"wordCount\":548,\"publisher\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/Soutenance-TBI-1.png\",\"keywords\":[\"Equipe TIM\"],\"articleSection\":[\"Ev\u00e9nement\",\"Soutenance\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/\",\"url\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/\",\"name\":\"Soutenance de th\u00e8se Elise VIAU | TBI, Toulouse Biotechnology Institute\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/Soutenance-TBI-1.png\",\"datePublished\":\"2026-02-24T07:00:05+00:00\",\"dateModified\":\"2026-03-05T10:11:21+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/Soutenance-TBI-1.png\",\"contentUrl\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/Soutenance-TBI-1.png\",\"width\":1920,\"height\":1080},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/soutenance-de-these-elise-viau\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Soutenance de th\u00e8se Elise VIAU\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#website\",\"url\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/\",\"name\":\"TBI, Toulouse Biotechnology Institute\",\"description\":\"Bio &amp; Chemical Engineering\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#organization\"},\"alternateName\":\"TBI, Toulouse Biotechnology Institute\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#organization\",\"name\":\"TBI - Toulouse Biotechnology Institute\",\"url\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/i0.wp.com\\\/www.toulouse-biotechnology-institute.fr\\\/wp-content\\\/uploads\\\/2021\\\/11\\\/100LOGO-TBITransp-BD.png?fit=100%2C56&ssl=1\",\"contentUrl\":\"https:\\\/\\\/i0.wp.com\\\/www.toulouse-biotechnology-institute.fr\\\/wp-content\\\/uploads\\\/2021\\\/11\\\/100LOGO-TBITransp-BD.png?fit=100%2C56&ssl=1\",\"width\":100,\"height\":56,\"caption\":\"TBI - Toulouse Biotechnology Institute\"},\"image\":{\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/TBI-Toulouse-Biotechnology-Institute-Bio-Chemical-Engineering-360428497952306\",\"https:\\\/\\\/x.com\\\/TBI_Biotech\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/#\\\/schema\\\/person\\\/925c08c7f4d7092aa300f21b872c6dfe\",\"name\":\"Christelle\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a462b358930aacca9abe665c74c4b67c3548729245baf256d2b793f4bf92d24f?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a462b358930aacca9abe665c74c4b67c3548729245baf256d2b793f4bf92d24f?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a462b358930aacca9abe665c74c4b67c3548729245baf256d2b793f4bf92d24f?s=96&d=mm&r=g\",\"caption\":\"Christelle\"},\"sameAs\":[\"http:\\\/\\\/v2tbi.christelle-labruyere.com\"],\"url\":\"https:\\\/\\\/www.toulouse-biotechnology-institute.fr\\\/en\\\/author\\\/christelle\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Soutenance de th\u00e8se Elise VIAU | TBI, Toulouse Biotechnology Institute","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-elise-viau\/","og_locale":"en_GB","og_type":"article","og_title":"Soutenance de th\u00e8se Elise VIAU | TBI, Toulouse Biotechnology Institute","og_description":"24 f\u00e9vrier 2026","og_url":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-elise-viau\/","og_site_name":"TBI, Toulouse Biotechnology Institute","article_publisher":"https:\/\/www.facebook.com\/TBI-Toulouse-Biotechnology-Institute-Bio-Chemical-Engineering-360428497952306","article_published_time":"2026-02-24T07:00:05+00:00","article_modified_time":"2026-03-05T10:11:21+00:00","og_image":[{"width":1920,"height":1080,"url":"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2026\/02\/Soutenance-TBI-1.png","type":"image\/png"}],"author":"Christelle","twitter_card":"summary_large_image","twitter_creator":"@TBI_Biotech","twitter_site":"@TBI_Biotech","twitter_misc":{"Written by":"Christelle","Estimated reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/#article","isPartOf":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/"},"author":{"name":"Christelle","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#\/schema\/person\/925c08c7f4d7092aa300f21b872c6dfe"},"headline":"Soutenance de th\u00e8se Elise VIAU","datePublished":"2026-02-24T07:00:05+00:00","dateModified":"2026-03-05T10:11:21+00:00","mainEntityOfPage":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/"},"wordCount":548,"publisher":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#organization"},"image":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/#primaryimage"},"thumbnailUrl":"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2026\/02\/Soutenance-TBI-1.png","keywords":["Equipe TIM"],"articleSection":["Ev\u00e9nement","Soutenance"],"inLanguage":"en-GB"},{"@type":"WebPage","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/","url":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/","name":"Soutenance de th\u00e8se Elise VIAU | TBI, Toulouse Biotechnology Institute","isPartOf":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/#primaryimage"},"image":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/#primaryimage"},"thumbnailUrl":"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2026\/02\/Soutenance-TBI-1.png","datePublished":"2026-02-24T07:00:05+00:00","dateModified":"2026-03-05T10:11:21+00:00","breadcrumb":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/#primaryimage","url":"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2026\/02\/Soutenance-TBI-1.png","contentUrl":"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2026\/02\/Soutenance-TBI-1.png","width":1920,"height":1080},{"@type":"BreadcrumbList","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/soutenance-de-these-elise-viau\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.toulouse-biotechnology-institute.fr\/"},{"@type":"ListItem","position":2,"name":"Soutenance de th\u00e8se Elise VIAU"}]},{"@type":"WebSite","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#website","url":"https:\/\/www.toulouse-biotechnology-institute.fr\/","name":"TBI, Toulouse Biotechnology Institute","description":"Bio &amp; Chemical Engineering","publisher":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#organization"},"alternateName":"TBI, Toulouse Biotechnology Institute","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.toulouse-biotechnology-institute.fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#organization","name":"TBI - Toulouse Biotechnology Institute","url":"https:\/\/www.toulouse-biotechnology-institute.fr\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#\/schema\/logo\/image\/","url":"https:\/\/i0.wp.com\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2021\/11\/100LOGO-TBITransp-BD.png?fit=100%2C56&ssl=1","contentUrl":"https:\/\/i0.wp.com\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2021\/11\/100LOGO-TBITransp-BD.png?fit=100%2C56&ssl=1","width":100,"height":56,"caption":"TBI - Toulouse Biotechnology Institute"},"image":{"@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/TBI-Toulouse-Biotechnology-Institute-Bio-Chemical-Engineering-360428497952306","https:\/\/x.com\/TBI_Biotech"]},{"@type":"Person","@id":"https:\/\/www.toulouse-biotechnology-institute.fr\/#\/schema\/person\/925c08c7f4d7092aa300f21b872c6dfe","name":"Christelle","image":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/secure.gravatar.com\/avatar\/a462b358930aacca9abe665c74c4b67c3548729245baf256d2b793f4bf92d24f?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/a462b358930aacca9abe665c74c4b67c3548729245baf256d2b793f4bf92d24f?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a462b358930aacca9abe665c74c4b67c3548729245baf256d2b793f4bf92d24f?s=96&d=mm&r=g","caption":"Christelle"},"sameAs":["http:\/\/v2tbi.christelle-labruyere.com"],"url":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/author\/christelle\/"}]}},"jetpack_featured_media_url":"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2026\/02\/Soutenance-TBI-1.png","_links":{"self":[{"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/posts\/17447","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/comments?post=17447"}],"version-history":[{"count":7,"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/posts\/17447\/revisions"}],"predecessor-version":[{"id":17455,"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/posts\/17447\/revisions\/17455"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/media\/17448"}],"wp:attachment":[{"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/media?parent=17447"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/categories?post=17447"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/wp-json\/wp\/v2\/tags?post=17447"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}