{"id":15762,"date":"2025-03-12T14:46:03","date_gmt":"2025-03-12T13:46:03","guid":{"rendered":"https:\/\/www.toulouse-biotechnology-institute.fr\/?p=15762"},"modified":"2025-03-20T14:51:32","modified_gmt":"2025-03-20T13:51:32","slug":"avancee-majeure-en-biologie-une-ia-generative-hybride-concoit-de-nouvelles-molecules","status":"publish","type":"post","link":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/avancee-majeure-en-biologie-une-ia-generative-hybride-concoit-de-nouvelles-molecules\/","title":{"rendered":"Major breakthrough in biology: hybrid generative AI designs new molecules"},"content":{"rendered":"
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PRESS RELEASE - Predict protein structure, create new ones. Protein design is a field of research that is undergoing a revolution thanks to the possibilities offered by AI, with the aim of designing new proteins and enzymes with direct applications in health and the environment. INRAE mathematics researchers have developed an AI that combines learning and reasoning. This hybrid AI is capable of designing proteins according to rules learned through deep learning, but also derived from physics or made explicit by designers. These results contribute to the panorama of protein design methods presented in the journal Nature Reviews Methods Primers.<\/p>

Published on March 03, 2025 on the INRAE website<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tRead the press release on the INRAE website<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\tAlbanese K.I., Barbe S., Tagami S. et al. (2025). Computational Protein Design. Nature Reviews Methods Primers, DOI : https:\/\/doi.org\/10.1038\/s43586-025-00383-1 \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\tSophie BARBE\n\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

COMMUNIQU\u00c9 DE PRESSE – Pr\u00e9dire la structure des prot\u00e9ines, en cr\u00e9er de nouvelles. Le design des prot\u00e9ines est un domaine de recherche en pleine r\u00e9volution gr\u00e2ce aux possibilit\u00e9s offertes par l\u2019IA, avec en ligne de mire la conception de nouvelles prot\u00e9ines et enzymes avec des applications directes en sant\u00e9 et en environnement. Retour sur ces […]<\/p>\n","protected":false},"author":1,"featured_media":15763,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12],"tags":[35],"class_list":["post-15762","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-resultat-scientifique","tag-equipe-cimes"],"yoast_head":"\nAvanc\u00e9e majeure en biologie : une IA g\u00e9n\u00e9rative hybride con\u00e7oit de nouvelles mol\u00e9cules | TBI, Toulouse Biotechnology Institute<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/avancee-majeure-en-biologie-une-ia-generative-hybride-concoit-de-nouvelles-molecules\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Avanc\u00e9e majeure en biologie : une IA g\u00e9n\u00e9rative hybride con\u00e7oit de nouvelles mol\u00e9cules | TBI, Toulouse Biotechnology Institute\" \/>\n<meta property=\"og:description\" content=\"COMMUNIQU\u00c9 DE PRESSE – Pr\u00e9dire la structure des prot\u00e9ines, en cr\u00e9er de nouvelles. 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Retour sur ces […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/avancee-majeure-en-biologie-une-ia-generative-hybride-concoit-de-nouvelles-molecules\/\" \/>\n<meta property=\"og:site_name\" content=\"TBI, Toulouse Biotechnology Institute\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/TBI-Toulouse-Biotechnology-Institute-Bio-Chemical-Engineering-360428497952306\" \/>\n<meta property=\"article:published_time\" content=\"2025-03-12T13:46:03+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-20T13:51:32+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.toulouse-biotechnology-institute.fr\/wp-content\/uploads\/2025\/03\/proteine_ordi_bnicolas.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1100\" \/>\n\t<meta property=\"og:image:height\" content=\"400\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" 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