{"id":15185,"date":"2024-11-14T09:00:04","date_gmt":"2024-11-14T08:00:04","guid":{"rendered":"https:\/\/www.toulouse-biotechnology-institute.fr\/?p=15185"},"modified":"2024-11-14T10:18:20","modified_gmt":"2024-11-14T09:18:20","slug":"soutenance-de-these-amel-chammam","status":"publish","type":"post","link":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-amel-chammam\/","title":{"rendered":"PhD defence Amel Chammam"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"15185\" class=\"elementor elementor-15185\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9b2a775 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9b2a775\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9d57596\" data-id=\"9d57596\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5a0fb5c elementor-widget elementor-widget-text-editor\" data-id=\"5a0fb5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>I&#8217;m pleased to invite you to <strong>my thesis defense<\/strong> on Tuesday, <strong>December 10th, at 9 a.m<\/strong>. in room GP3E 228 Capdeville (VP-TB-F) 30 (INSA, 135 Avenue de Rangueil 31400 Toulouse).<\/p><p>The <strong>title<\/strong> of my thesis is &#8220;<strong>Valorization of pinecones from the genus Pinus: Intensification of extraction processes &amp; identification of bioactive molecules<\/strong>&#8220;.<\/p><p>\u00a0<\/p><p><strong>Jury composition:<\/strong><\/p><ul><li>Mme Caroline REMOND, Rapportrice, University of Reims Champagne-Ardenne<\/li><li>M. Fethi ZAGROUBA, Rapporteur, University of\u00a0Carthage<\/li><li>M. Jalloul BOUAJILA, Examinateur, University of Toulouse III &#8211; Paul Sabatier<\/li><li>M. Hichem BEN JANNET, Examinateur, University of Monastir<\/li><li>M. Mehrez ROMDHANE, thesis supervisor, University of Gabes<\/li><li>M. Luc FILLAUDEAU, thesis supervisor, University of Toulouse &#8211; INRAE<\/li><\/ul><p><strong>Abstract:<\/strong><\/p><p>Considering the circular economy and biomass valorization, this doctoral project focuses on the valorization of Tunisian pine cones (particularly the petal and core fractions) in the cosmetic and pharmaceutical industries. Initially, extraction was carried out via maceration using various organic solvents of increasing polarity (cyclohexane, ethyl acetate, and methanol) and water, from the petals and cores of <em>P. halepensis <\/em>(PA), <em>P. brutia<\/em> (PB), and <em>P. pinea<\/em> (PP). The effects of particle size, ranging from 120 to 1400 \u00b5m, and suspension concentration, ranging from 0 to 170 g mh\/L<sub>susp<\/sub>, were studied on rheological behavior, sedimentation kinetics, extraction yield and kinetics, as well as chemical analyses and bioactivities for the petals of P. halepensis. Models describing the rheological behavior and extraction kinetics were proposed to address bioprocess scaling challenges and optimize process control.<\/p><p>Additionally, a second part of this project involved Soxhlet extraction with different solvents (ethanol and hexane) and supercritical fluid extraction (SCO<sub>2<\/sub>), evaluating various process parameters, including extraction time, pressure, co-solvent addition, and particle size. Finally, a comparative study was conducted between the different extraction techniques, matrices, and operating conditions, based on extraction yield, physical limitations, chemical analyses, and bioactivities, to select a matrix of interest and optimize the extraction of bioactive compounds.<\/p><p>This approach highlights the importance of valorizing pine cones, as a forest residue, to support the circular economy. Furthermore, integrating a green and intensified process, makes it possible to extract high-quality antioxidant compounds at a low cost, while promoting environmental sustainability.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>December 10, 2024<\/p>","protected":false},"author":1,"featured_media":15186,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,75],"tags":[25],"class_list":["post-15185","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evenement","category-soutenance","tag-equipe-tim"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Soutenance de th\u00e8se Amel CHAMMAM | TBI, Toulouse Biotechnology Institute<\/title>\n<meta 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