{"id":13238,"date":"2023-09-07T07:36:00","date_gmt":"2023-09-07T05:36:00","guid":{"rendered":"https:\/\/www.toulouse-biotechnology-institute.fr\/?p=13238"},"modified":"2023-09-07T14:38:41","modified_gmt":"2023-09-07T12:38:41","slug":"soutenance-de-these-juan-camilo-acosta-pavas","status":"publish","type":"post","link":"https:\/\/www.toulouse-biotechnology-institute.fr\/en\/soutenance-de-these-juan-camilo-acosta-pavas\/","title":{"rendered":"PhD defence \t\nJuan Camilo Acosta Pavas"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"13238\" class=\"elementor elementor-13238\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-665a8eb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"665a8eb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9562ba6\" data-id=\"9562ba6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-27fc76e elementor-widget elementor-widget-text-editor\" data-id=\"27fc76e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Th\u00e8se intitul\u00e9e : Modeling and dynamic optimization of biomethanation: dynamic and multiphysics study of biological couplings and gas-liquid transfers to optimize the operation of industrial reactors<\/strong><\/p><p>Travaux dirig\u00e9s par J\u00e9r\u00f4me Morchain et C\u00e9sar Arturo Aceves Lara<\/p><p>PhD defence\u00a0<em><strong>lundi 11 septembre 2023\u00a0<\/strong><\/em>at 2:00 pm.<br \/>Lieu : \u00a0 135 Avenue de Rangueil, 31400 Toulouse<br \/>Salle : 401<\/p><p><strong>Jury composition:\u00a0<\/strong><\/p><table><tbody><tr><td width=\"302\"><p>J\u00e9r\u00f4me MORCHAIN<\/p><\/td><td width=\"302\"><p>Directeur de th\u00e8se<\/p><\/td><\/tr><tr><td width=\"302\"><p>C\u00e9sar Arturo ACEVES LARA<\/p><\/td><td width=\"302\"><p>Co-directeur de th\u00e8se<\/p><\/td><\/tr><tr><td width=\"302\"><p>Jean-Philippe STEYER<\/p><\/td><td width=\"302\"><p>Rapporteur<\/p><\/td><\/tr><tr><td width=\"302\"><p>C\u00e9line CASENAVE<\/p><\/td><td width=\"302\"><p>Rapporteure<\/p><\/td><\/tr><tr><td width=\"302\"><p>Arnaud COCKX<\/p><\/td><td width=\"302\"><p>Examinateur<\/p><\/td><\/tr><tr><td width=\"302\"><p>Carlos Eduardo ROBLES RODRIGUEZ<\/p><\/td><td width=\"302\"><p>Examinateur<\/p><\/td><\/tr><tr><td width=\"302\"><p>Oscar Andr\u00e9s PRADO RUBIO<\/p><\/td><td width=\"302\"><p>Examinateur<\/p><\/td><\/tr><tr><td width=\"302\"><p>David GRIOL BARRES<\/p><\/td><td width=\"302\"><p>Examinateur<\/p><\/td><\/tr><\/tbody><\/table><p><strong>\u00a0<\/strong><\/p><p><strong>R\u00e9sum\u00e9\u00a0:<\/strong>\u00a0\u00a0<\/p><p>This thesis aims at studying biological methanation to find the optimal conditions to produce high-purity biomethane as a value-added product. The objective is addressed from a modeling point of view, based on the use of model-based control strategies and data-driven soft sensors. A bibliography synthesis was carried out to set the theoretical framework that includes dynamic models, control strategies, and monitoring tools applied to biological methanation. An extension of the Anaerobic Digestion Model No.1 (ADM1_ME) was proposed to describe the dynamics of the biological methanation process with the use of syngas (H<sub>2<\/sub>, CO<sub>2,<\/sub> and CO) as substrate. The variation of the volumetric mass transfer coefficient is considered as a function of two types of reactors, a bubble column reactor (BCR) and a Continuous Stirred Tank Reactor (CSTR). The ADM1_ME was accurately calibrated and validated in different operating conditions using experimental data from the literature. A Multi-Objective Dynamic Optimization (MODO) strategy was proposed to optimize the biological methanation performance. The MODO strategy was designed to consider three different objective functions to maximize: (i) yield \u00a0and productivity \u00a0of methane, (ii) \u00a0and \u00a0simultaneously complemented by a switch to maximize acetate yields \u00a0and productivities , and (iii) economic optimality in terms of \u00a0and . The results demonstrated the feasibility of the MODO strategy and its robustness to switch between products of interest and the key role of the manipulated variables (<em>i.e.<\/em>, inlet liquid and gas flow rates) in the biological methanation process. Furthermore, data-driven soft sensors were applied to detect deviations from the optimal operation points when disturbances occurred in the manipulated variables. Specifically, Support Vector Machine (SVM) showed promising results and a potential application by using 2D visualizations constructed by pair of features.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>September 11, 2023<\/p>","protected":false},"author":1,"featured_media":13239,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,75],"tags":[25],"class_list":["post-13238","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evenement","category-soutenance","tag-equipe-tim"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Soutenance de th\u00e8se Juan Camilo Acosta Pavas | TBI, Toulouse Biotechnology Institute<\/title>\n<meta name=\"robots\" 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