Research

Our team develops methods of nuclear magnetic resonance in hte following framework :

  • follow the incorporation of isotopes in metabolites,,
  • study enzyme dynamics,
  • study the interaction between metabolites and enzymes.. 

 

Those methods are applied to gain insight in metabolic networks and their regulation in different organisms. The study of enzyme dynamics gives access to dynamics as a novel parameter in the rational engineering of novel enzymes.

 

Isolated enzyme at work 

We use NMR spectroscopy to understand how enzymes work. 

References

 

Investigations on the Determinants Responsible for Low Molar Mass Dextran Formation by DSR-M Dextransucrase

Claverie, M., Cioci, G., Vuillemin, M., Monties, N., Roblin, P., Lippens, G., Remaud Simeon, M., Moulis, C. . ACS Catalysis, 7 (10), 7106-7119.