Metabolic engineering

Research objectives


 Engineer microorganisms for the

–Production of high added value chemical synthons

–Production of food supplements and novel pharmaceutical compounds.


3 teams that

–Develop and use Synthetic Biology approaches to rewire existing or construct new metabolic pathways

–Use Systems Biology tools to analyze, better understand and further tune synthetic metabolic networks

3 teams with complimentary approaches
  • Genome engineering, functional genomics, functional genetics
  • Regulation of metabolic networks, metabolic flux analysis
  • Enzyme discovery and engineering

Several model organisms

  • Escherichia coli
  • Clostridium acetobutylicum
  • Phaeodactylum tricornutum
  • Saccharomyces cerevisiae